Eli Lilly has agreed to buy psychedelic drugmaker AtaiBeckley in a deal worth up to $2.8 billion upfront, sending ATAI stock up 34% in premarket trading on Thursday.
AtaiBeckley was trading at $7.19 premarket, up 34.2%. The stock initially jumped more than 50% after Bloomberg reported late Wednesday that Lilly was negotiating a deal at a premium.
Lilly is paying $6.75 per share in cash. On top of that, AtaiBeckley shareholders could receive up to $2.50 more per share if certain development and regulatory milestones are hit.
The $6.75 per share price represents a 40% premium to AtaiBeckley’s 30-day volume-weighted average price.
ATAI stock was already up 31% year-to-date through Wednesday’s close before this deal was announced.
A big chunk of that 2025 gain came in April, when ATAI jumped 22% in a single day after President Trump signed a directive to speed up FDA review of psychedelic drugs for serious mental illnesses.
AtaiBeckley’s lead program is BPL-003, an intranasal formulation of 5-MeO-DMT being developed for treatment-resistant depression.
The deal lifted other names in the psychedelic space too. GH Research rose 15%, Compass Pathways gained 7%, Definium Therapeutics climbed 6%, and Enveric Biosciences added 3% in premarket trading.
BMO Capital Markets analyst Evan Seigerman noted that while the deal could exceed $2 billion, ongoing talks with other pharmaceutical companies could push the takeout price even higher.
RBC Capital Markets analyst Brian Abrahams said the psychedelic sector is likely to keep rallying and is moving toward the mainstream.
This deal fits a pattern for Lilly, which has been active on the acquisition front — particularly in neuroscience. The company’s most recent big move was the $7.8 billion buyout of sleep-disorder drugmaker Centessa Pharmaceuticals.
Lilly stock was largely flat on Thursday, up just 0.3% premarket.
AtaiBeckley’s market cap stood at $1.97 billion as of Wednesday’s close, according to LSEG data.
The combined upfront and milestone consideration puts the total potential deal value at $9.25 per share.
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