Wave Life Sciences Ltd stock touched $15.75, marking its highest price in 52 weeks. The biotech company reached this peak despite posting a 50.95% decline over the past year.
The stock jump follows promising data from the company’s INLIGHT clinical trial. The study tested WVE-007 as a potential obesity treatment. Results showed strong outcomes after just three months.
Participants received a single 240mg dose of WVE-007. They experienced a 9.4% reduction in visceral fat. Total body fat decreased by 4.5%. Lean mass increased by 3.2%.
Today we shared exciting interim data from our ongoing INLIGHT trial of WVE-007 (INHBE GalNAc-siRNA) for obesity. A single dose resulted in an improvement in body composition with fat loss similar to GLP-1 at three months without muscle loss. See the presentation:… pic.twitter.com/CLD48sOz2K
— Wave Life Sciences (@WaveLifeSci) December 8, 2025
The placebo group showed no meaningful changes in these measurements. The trial included healthy overweight and obese participants.
The data confirmed earlier findings from a company research event. Researchers achieved these results at what they consider a minimal therapeutic dose.
Wave Life Sciences reported third-quarter 2025 financial results. Revenue came in at $7.6 million. This fell short of analyst expectations of $12.89 million.
The company did show improvement in managing losses. Net loss totaled $53.9 million. This represented an improvement from the $61.8 million loss in the previous year.
The company maintains a strong cash position relative to debt. However, financial data indicates rapid cash burn. Wave Life Sciences remains unprofitable.
The stock trades at a price-to-sales ratio of 26.35. This sits well above industry averages. Market capitalization stands at approximately $2.96 billion.
Operating margin sits at -124.46%. Net margin reaches -111.64%. Earnings per share came in at -$0.75 for the reporting period.
Analysts continue rating Wave Life Sciences as Outperform. Price targets range from $9 to $36. The average analyst target price stands at $19.94.
Institutional investors hold 90.19% of outstanding shares. Insider ownership accounts for 4.23% of the company.
The company operates a platform called PRISM. This technology combines multiple RNA medicine approaches. These include RNA editing, antisense silencing, and RNA interference.
Wave Life Sciences targets both rare and common diseases. Current programs focus on alpha-1 antitrypsin deficiency, obesity, Duchenne muscular dystrophy, and Huntington’s disease.
The company plans to release additional data from the Phase 1 INLIGHT trial. An investor conference call and webcast is scheduled for December 8.
Higher dose studies over longer periods are underway. Researchers aim to build on the initial three-month findings. The activin E reductions observed at 240mg doses matched preclinical predictions.
The post Wave Life Sciences (WVE) Stock Reaches 52-Week High on Positive Obesity Trial Data appeared first on CoinCentral.
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